Review
paper Title:
Toxic effects of rubber tire wear compounds 6PPD and 6PPDQ t

Review
paper Title:
Toxic effects of rubber tire wear compounds 6PPD and 6PPDQ to aquatic organisms.
Table of contents:
Highlights
Graphical abstract
Abstract
1.    
Introduction
1.1.  Occurrence
1.2.  Chemistry and transformation products
1.3.  Factors affecting the transformation.
1.4.  Biotransformation in aquatic organisms
Figure.1. Transformation from 6PPD to
6PPDQ
Figure.2. Biotransformation in aquatic
organisms
2.    
Potential
toxicological effects of 6PPD or 6PPDQ on aquatic organisms (Developmental toxicity,
neurotoxicity, reproductive toxicity, cardiotoxicity, and others)
Table: List of 6PPD or 6PPDQ exposure
studies in aquatic organisms
3.    
Different
mechanisms of toxicity.
4.    
Conclusion
and future perspectives.